QPCR Data Relevant to Endomesoderm Network

Perturbation Ct:[Ub-C]-[Ub-Exp]

May 18, 2010

Ub, ubiquitin mRNA control used for internal standardization; CT, cycle no. at threshold; C, control embryo sample; Exp, sample from perturbed embryos. The quantity of transcript at any point in the reaction is I(1.94CT), where I is the initial amount in the reaction mixture. A positive number means the number of transcripts is increased by the perturbation; a negative number means the number of transcripts is decreased. Data are listed that are considered significant where significant means more than three-fold increase or decrease from control transcript levels (normalized CT difference from control is <-1.6 or >+1.6). Smaller effects are shown as "NS", except where individual NS data are included together with other significant measurements to display scatter or inconsistencies amongst different batches of cDNA. Commas separate replicate measurements in the same cDNA batch; slashes indicate different batches of cDNA from independent experiments.

Abbreviations
MASO: Morpholino-substituted antisense oligo nucleotide
MOE: Messenger RNA overexpression
EN: Engrailed repressor domain

Gene

Perturbation

12-16 h

17-21 h

23-28 h

30-36 h

41-48 h

60-72 h

Data of:

alx124

Pmar1 MOE

+4.4/+4.7


+3.2/+5.8




K. Young,

L. Vega &

P. Oliveri

Cad MOE

-5.3/-4.8


-5.2/-3.2




K. Young,

L. Vega &

P. Oliveri

Pmar1 MOE +

Cad MOE

+3.1/+3.9


+4.3/+7.5




K. Young,

L. Vega &

P. Oliveri

Pmar1-En

+2.4/+2.3


+2.0/+2.9




K. Young,

L. Vega &

P. Oliveri

Pmar1-En +

Cad MOE

+2.5


+2.6/+4.3




K. Young,

L. Vega &

P. Oliveri

Alx1 MASO


+1.9,+1.7/+1.6/

NS/+2.2/NS/NS/

NS

NS,NS/+1.9/

NS/NS/NS/NS/

NS




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Soxb1 MOE26

-3.1,-3.1

NS,NS

NS,NS




L. Chen

Ets1 MASO

NS/NS

NS,NS/NS/

NS/NS/NS

-3.6/-1.8/-2.0,

NS/-1.7/-1.95/

-2.58/NS




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Snail MASO48



NS/NS/NS




S. Wu &

D. McClay

Tgif MASO


NS/NS/NS/

NS/NS/NS/NS/

NS

(-2.41/NS/

-2.49/NS/NS/NS/

-2.05/NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Tel MASO


+1.63/NS/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/+2.0/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


+2.02/+2.27/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


+3.11/NS/+3.34/

NS/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Blimp1b MASO


NS/NS/+1.67/

+1.94/NS

(NS/NS/NS/

NS/NS[24 h])

(NS/NS/NS/

NS/NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

+1.83

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

N MASO


NS/NS/NS

(NS/NS/NS/

+1.65[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/-1.91/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(NS/-1.62/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

blimp1a

Brn1/2/4 MASO





-4.4


C. Yuh

blimp1b

Blimp1b MASO

+2.1,+1.8

NS/NS/NS/

NS/NS/NS/NS/

+1.57/+1.77/NS

(NS/+1.86/NS/

+1.86/+1.58[24 h])

(NS/+1.83/NS/

NS[27 h])

NS/NS


+2.3


C. Livi,

I. Peter &

J. Yun

Blimp1b-En

-4.0,-4.8

-7.8,-8.0

-7.4,-5.0/-5.3/

-2.1,-2.2




C. Livi

Cad MOE

-5.9/-4.8/-4.2

-4.6/-7.8

-5.1/-14.3/

-4.6




A. Ransick,

T. Minokawa,

P. Oliveri &

L. Vega

Otx-En

-2.3/-1.6

NS/NS/NS

-2.5/-3.3/NS




A. Ransick &

T. Minokawa

Eve MASO

NS/NS/NS

NS/-2.44/NS

(-2.12/NS/

-3.34[24 h])

(-3.13/-3.69/

-1.74[27 h])

-1.9,-2.2




A. Ransick,

C. Livi &

I. Peter

Pmar1 MOE



-2.6




P. Oliveri &

L. Vega

Wnt8 MASO

(NS,-2.6,

-2.1 (12 h)[12 h])

(-2.8,NS,

-3.1 (16 h)[16 h])






J. Smith

Tgif MASO


NS/NS/NS/

NS

(-1.72/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

N MASO


+2.35/+1.94/NS

(+2.0/NS/NS/NS[24 h])

(+1.85/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

-1.94

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

GataE MASO


NS/NS/NS/

NS

(NS/NS/NS/

-2.22[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/-1.93/

-1.47

(-2.05/-2.0/

-1.86[24 h])

(-1.77/-1.6/

-2.23[27 h])




I. Peter

bra

GataE MASO


-2.8,-2.4/-2.8,

-3.2/-1.6

-1.6,NS/-3.3,

-3.2/-2.1,-2.2

-2.8



P. Y. Lee &

C. Yuh

Blimp1b-En

-2.0,-3.3

-9.0,-9.0

-5.2,-5.5/-5.0/

-2.3




C. Livi

FoxA MASO


NS/NS

(NS[24 h])

(NS[27 h])

NS/NS/NS

+1.6/+1.6/+2.1

NS/NS


P. Oliveri,

I. Peter &

J. Yun

Cad MOE

NS/NS

-4.7/-2.1

-4.4/-3.0/-2.4




A. Ransick,

T. Minokawa &

C. Livi

Elk-En



-3.2,-2.2,-4.1




M. Arnone

Otx-En


-2.5/-3.4/-4.3/

-8.2

-2.4/-2.0/-5.2/

-4.6




A. Ransick &

T. Minokawa

Hox11/13b MASO


-3.0/-2.18/

-2.52

(-2.21/-2.11/

NS[24 h])

(-1.9/-3.34/

-2.19[27 h])

+1.9/NS


NS


C. Arenas-Mena &

I. Peter

Soxb1 MOE26


NS,NS

-2.9,-3.4




L. Chen

Tgif MASO


NS/NS/NS/

NS

(NS/-1.74/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


-1.66/NS/NS/

NS

(NS/NS/-2.87/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Eve MASO

NS/NS

NS/NS

(NS/-1.75/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Brn1/2/4

Otxb1/2 MASO




NS

-1.7/NS/-2.5/

-1.7/NS


C. Yuh

Dac MASO


NS/NS

(NS/NS[24 h])

(-3.06/NS[27 h])




I. Peter &

J. Yun

Tgif MASO


NS/NS

(NS/NS[24 h])

(-2.48/-2.83[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/-2.47/

-2.38[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS

(NS/NS/NS[24 h])

(-1.73/-3.24/

-2.19[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS

(NS/NS[24 h])

(-2.14/-3.77[27 h])




I. Peter &

J. Yun

GataE MASO


NS/NS/NS

(NS/NS/NS[24 h])

(-2.86/-1.74/

-2.47[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS

(NS/NS[24 h])

(-2.63/-2.6[27 h])




I. Peter &

J. Yun

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/NS[24 h])

(-1.88/-2.72/

-2.01[27 h])




I. Peter

Otxa MASO


NS/NS/NS

(NS/NS/NS[24 h])

(-1.66/-2.78/

-2.82[27 h])




I. Peter

SoxC MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/NS/-2.05[27 h])




I. Peter

OtxHD MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/-1.36/

-2.03[27 h])




I. Peter

capk

Bra MASO1



-1.7




J. Rast

cyclophillin

Pmar1 MOE

+3.3


+5.5




P. Oliveri

Pmar1-En

NS


+3.4




P. Oliveri

Dri MASO

-2.6/-2.7

-3.6/NS/-1.8/

NS/NS/NS

NS/NS/NS




G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

Dri-En


-1.8/-2.4





G. Amore

Gsc MASO38


-2.4,NS

NS/-1.9




G. Amore

Soxb1 MOE26



-3.6,-7.3/-2.2,

-1.7




L. Chen

Soxb1-En



-3.9,-2.6




L. Vega &

W. Chiu

Ets1 MASO


-3.12,-3.03/

NS/-1.84/NS/

-2.17/-4.04

-3.02,-3.6/

-3.25/NS/-2.39/

-2.34/-2.56/-2.07




P. Oliveri,

Q. Tu &

J. Yun

Alx1 MOE


-2.56,-2.46/

NS

-2.81,-3.4/

NS/NS




P. Oliveri

Ets1 MASO +

Alx1 MOE


-5.31,-5.22/

-3.7

-5.47,-6.05/

-3.69/-3.57




P. Oliveri

Hex MASO


NS/NS/NS

NS/-1.91/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

NS/-1.68

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

dac

Dac MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(+1.61/+1.64/NS/

+1.67[27 h])




I. Peter &

J. Yun

Otxa MASO


NS/+1.97/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/NS[24 h])

(NS/-1.64/NS[27 h])




I. Peter

delta

Cad MOE

-3.3/-3.9

-1.6/NS

NS/-1.9




A. Ransick &

T. Minokawa

Pmar1 MOE

+1.8/+3.2


+2.6/+2.6




P. Oliveri

Pmar1-En

+1.8/+2.0


+3.1/+2.0




P. Oliveri

Soxb1 MOE26

-3.7,-3.3

-1.8,-2.4

-2.3,-2.2/NS




L. Chen

Tel MASO


+1.81/NS/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/NS/NS

+1.63/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/NS/NS

NS/+1.78/NS




Q. Tu,

P. Oliveri &

J. Yun

N MASO


NS/-1.74/NS

(NS/NS/NS/

-1.92[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Eve MASO

NS/NS

NS/NS/NS

(-1.62/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Otxa MASO


NS/+1.82/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

dpt

Bra MASO1



-6.8




J. Rast

DnN MOE8


-1.7





C. Calestani

Elk-En5



-2.1,-2.2,-4.6




M. Arnone

Krl MASO18, 26

-3.8/-3.8

NS/NS

-3.1/-2.8/-2.0,

-1.6




C. Livi

Gcm MASO


-2.6

-5.7/-3.6




A. Ransick

dri

Pmar1 MOE

+3.6


+6.7




P. Oliveri

Pmar1-En

+2.4


+7.2




P. Oliveri

Dri MASO20


NS/NS/NS/

NS/NS

NS/NS/NS/

NS/NS

-1.8/-4.5



G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

Alx1 MASO


-4.8,-3.6/-4.1/

-3.1/-1.8/

-3.88/-3.16/-4.26

-1.9/-2.9/NS/

-2.94/-3.4/

-2.91




P. Oliveri,

Q. Tu &

J. Yun

Ets1 MASO42


-2.8/-3.6/

-5.17,-5.83/-2.76/

-3.4,-2.58/-4.86/

-4.58/-2.58/-4.25

-1.7/-2.3/

-3.57,-2.12/-2.32/

-2.17,-2.97/-3.55/

-4.46/-3.12/-2.51




P. Oliveri,

Q. Tu &

J. Yun

Soxb1 MOE26


-3.0,-3.4

-2.9,-5.1




L. Chen

Tbr MASO42


NS/NS/+1.6/

+2.8/+2.0/NS/NS/

NS

+2.1/NS/+2.0/

+1.6/NS/NS




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Alx1 MOE


NS,NS/NS/

-2.44,-1.62

NS,NS/+2.26/

NS,NS




P. Oliveri

Ets1 MASO +

Alx1 MOE47


-1.85,-2.51/

NS/-5.53,-4.7

-3.39,-1.93/

NS/-4.41,-5.21




P. Oliveri

Tgif MASO


NS/NS/NS/

NS

NS/NS/NS/

-1.74




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-1.83/NS/

-2.17/NS/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

elk

Dac MASO


+2.49/+2.24/+1.52/

+1.46

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

NS/NS[24 h])

(NS/-3.42/NS/

NS/NS[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/-2.0/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


+1.51/NS/+1.72/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

N MASO


NS/NS/NS

(NS/NS/NS/

NS[24 h])

(NS/-2.06/NS/

NS[27 h])




I. Peter &

J. Yun

Myc MASO


+1.43/NS/NS/

+2.49

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Otxa MASO


NS/+2.59/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/NS[24 h])

(NS/-1.6/NS[27 h])




I. Peter

endo16

Otx-En

-1.6

-4.2

-3.1/-4.3/-6.6




A. Ransick &

T. Minokawa

GataE MASO


NS/NS/-2.6/

NS/NS/NS/NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])

-2.8,-3.5/-2.7,

-1.8

-2.3



P. Y. Lee,

C. Yuh,

I. Peter &

J. Yun

Hox11/13b MASO


-2.48/-1.75/

NS

(NS/NS/-2.73[24 h])

(NS/NS/-1.86[27 h])

NS/+1.6/+2.3



NS

C. Arenas-Mena &

I. Peter

Krl MASO18,26


-2.59/-2.57/

NS/NS

(NS/NS/NS/

-1.6[24 h])

(NS/-2.01/NS/

NS[27 h])

-4.0,-3.3/-2.5,

-2.5/NS




C. Livi,

L. Chen,

I. Peter &

J. Yun

Cad MOE10

-2.9/NS

-6.2/-2.3

-5.2/-2.2




A. Ransick &

T. Minokawa

FoxA MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])


-3.9,-2.7


K. Young,

P. Oliveri,

I. Peter &

J. Yun

N MASO


-1.71/NS/

-1.46

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])

-1.7 (29 h)



C. Calestani,

I. Peter &

J. Yun

Soxb1 MOE26


-4.5,-5.7

-7.6,-9.9




L. Chen

Blimp1b MASO


NS/-3.97/

-2.02/NS/-3.26

(-2.54/NS/

-3.27/NS/-3.8[24 h])

(NS/NS/-3.78/

-3.88/-1.9[27 h])




I. Peter &

J. Yun

Bra MASO


-1.82/-2.22/

-2.13/-2.4

(-2.01/NS/NS/

NS[24 h])

(NS/NS/-1.86/

NS[27 h])




I. Peter &

J. Yun

Dac MASO


NS/-2.12/

-2.93/-2.14

(NS/-1.97/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Eve MASO

NS/NS

NS/NS

(NS/NS/-1.86[24 h])

(-2.16/-1.78/

NS[27 h])




I. Peter

OtxHD MASO


-1.99/-1.75/

NS

(-2.03/NS/

-2.08[24 h])

(NS/NS/-1.97[27 h])




I. Peter

ephx

Bra MASO1



-3.8




J. Rast

erg

Hex MASO


-2.16/NS/

-1.94

NS/NS/-2.83




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


-1.86/-1.77/

-1.73/-2.25

-1.75/-1.99/

-2.46/NS




Q. Tu,

P. Oliveri &

J. Yun

Tbr MASO


NS/-1.55/

-2.79

-2.19/NS/

-3.19




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/-2.22/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


-1.64/NS/

-1.69/NS

NS/NS/NS/

-1.76




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/-2.37/

NS/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

ets1

Pmar1 MOE

NS


+5.4




P. Oliveri

Pmar1-En

NS


+4.5




P. Oliveri

Soxb1 MOE26

NS,NS

-2.0,-1.9

-2.1,-2.1




L. Chen

Snail MASO48



NS/NS,NS/

NS




S. Wu &

D. McClay

FoxN2/3 MASO


NS/+2.71/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


NS/+1.8/NS/

NS

NS/NS/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/+3.33/NS

NS/NS/+1.84




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


+2.85/NS/+3.47/

NS/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

eve

Blimp1b MASO

-2.3,-3.0

-1.6,-1.7,-2.7,

-2.3

NS/NS/NS




C. Livi,

I. Peter &

J. Yun

Blimp1b-En

NS

-4.4,-4.3

-2.8,-4.3/-5.3




C. Livi

Cad MOE

-6.3,-4.9/-3.9

-5.2,-4.0/-3.1

-5.5,-4.3/-4.6




A. Ransick &

T. Minokawa

Otx-En12



-2.9/NS




A. Ransick &

T. Minokawa

Soxb1 MASO26

-2.0/NS,-2.0,

-1.8/NS/-2.7


-2.1/NS

NS



C. Livi,

J. Rast &

K. Young

Hox11/13b MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])

NS/+1.9




C. Arenas-Mena &

I. Peter

Soxb1 MOE26, 41

-2.1,-1.9

NS,-3.0

-4.1,-4.2




L. Chen

Eve MASO

+2.8/NS/+3.45/

+3.31

+2.0/NS/+2.58/

+1.63/+2.39

(NS/+1.67/NS[24 h])

(NS/NS/+1.64[27 h])

NS/+2.2




A. Ransick,

C. Livi &

I. Peter

Pmar1 MOE



-4.7




P. Oliveri &

L. Vega

Cad MOE



-3.7




P. Oliveri &

L. Vega

Pmar1 MOE +

Cad MOE



-2.2




P. Oliveri &

L. Vega

Pmar1-En +

Cad MOE



-6.7




P. Oliveri &

L. Vega

Pmar1-En



-7.9




P. Oliveri &

L. Vega

Brn1/2/4 MASO





-5.7/NS


C. Yuh

ferritin

Hox11/13b MASO



NS/NS/+2.1



NS

C. Arenas-Mena

ficolin

Bra MASO1



-1.7




J. Rast

Pmar1 MOE

+4.0


+5.9




P. Oliveri

Pmar1-En

NS


+3.1




P. Oliveri

Dri MASO

-3.6/NS/-2.7,

-4.6

NS/NS/-1.8/

-2.5/NS/NS/NS

NS/NS/NS




G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

Dri-En


-4.6/-3.0





G. Amore

Hnf6 MASO


-2.9/-3.9/-3.2/

-3.4





O. Otim &

G. Amore

Gsc MASO38


-2.9/-2.4

-2.2/-2.0




G. Amore

Ets1 MASO


-2.56,-2.22/

-2.77/-3.33/-1.81/

-1.57/-2.36

-3.7/-2.0/

-2.32,-3.62/NS/NS/

-2.14/-3.92/

-2.85




P. Oliveri,

Q. Tu &

J. Yun

Soxb1 MOE26



-2.2,-4.2/-1.8




L. Chen

Soxb1-En



-5.0,-3.6




L. Vega &

W. Chiu

Alx1 MOE


NS,NS/+1.69

NS,-2.13/NS




Ets1 MASO +

Alx1 MOE


-5.0,-4.66/

NS

-2.42,-3.73/

-2.57




P. Oliveri

Hex MASO


-2.99/NS/

-2.68

NS/NS/-3.91




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/-2.08/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

SoxC MASO


-1.68/NS

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS

-1.64/NS/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Alx1 MASO


-2.46/NS/NS

NS/NS/-2.08




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-3.31/-1.66/

-5.47/NS/-1.73

NS/-1.79/

-1.86/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

foxa

GataE MASO


-2.1,-1.6/NS/

NS,-1.8/-2.34/

NS/NS/-2.35

(NS/-1.79/NS/

NS[24 h])

(NS/-1.57/

-2.81/-2.24[27 h])

-2.9,NS,-2.0/

-3.4,-3.1/-2.6




P. Y. Lee,

I. Peter &

J. Yun

FoxA MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])

+2.3/NS,+1.6/

+2.1

NS,+1.8

NS


P. Oliveri,

I. Peter &

J. Yun

Cad MOE

NS,-2.0,NS/

-2.2

NS,-4.1,-4.6/

-2.1

-2.6,-5.0,-4.6/

-4.9/-1.8




A. Ransick,

T. Minokawa &

C. Livi

Dri MASO2


NS/NS/NS

NS/NS/-2.47/

-2.41/NS

-2.3/-2.0/-2.0/

-2.0/-3.0/-2.0/

-2.0



G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

GataC MASO



-2.7




P. Oliveri &

J. Rast

DnN MOE3


-2.5/NS





C. Calestani

Elk-En4



-3.0,-3.7,-4.7




M. Arnone

Gsc MASO2



NS/NS

-3.2/NS/-3.0/

-3.0/-3.8/-3.0



G. Amore

Otx-En


NS/NS/-2.8

-3.3/NS/-4.1/

-2.8




A. Ransick &

T. Minokawa

Hox11/13b MASO


NS/-2.4/-1.64

(-2.64/-2.53/

-1.92[24 h])

(-1.88/NS/

-2.48[27 h])

+1.6/+1.6


NS


C. Arenas-Mena &

I. Peter

Soxb1 MOE26


NS,-5.1

-5.0,-5.4




L. Chen

Brn1/2/4 MASO





-4.4/NS/-3.7


C. Yuh

Ets1 MASO49


NS/-1.81/NS/

-2.86

-1.78/-1.76/

-1.88/-5.36




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


-2.64/-2.63/

NS/NS/NS/NS

(-4.1/-2.72/NS/

-1.95/NS/NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Erg MASO49


-2.47/-1.75/

-2.02/NS/-2.95

-2.28/-3.62/

-2.59/-2.29/NS




Q. Tu,

P. Oliveri &

J. Yun

Dac MASO


NS/NS/NS/

NS

(-3.13/NS/NS/

-2.14[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/-2.2/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


-1.75/NS/NS/

NS

(NS/-2.61/

-1.69/-1.48[24 h])

(NS/-1.48/NS/

-2.11[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/-2.39/NS/

NS/NS

(-1.5/NS/NS/

NS/-2.67[24 h])

(-3.28/NS/

-1.49/-1.9/-1.94[27 h])




I. Peter &

J. Yun

Krl MASO


NS/-2.29/NS/

NS

(-2.03/-1.67/

NS/NS[24 h])

(NS/-1.67/NS/

NS[27 h])




I. Peter &

J. Yun

Eve MASO

NS

NS/NS/+1.78

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

OtxHD MASO


-1.62/NS/NS

(-2.29/NS/NS[24 h])

(NS/-2.24/NS[27 h])




I. Peter

foxb

Blimp1b-En27


-5.0

-5.7




C. Livi

GataE MASO


-2.8/-2.4/-3.4,

-2.4/NS,+3.7/NS/

NS/NS

(NS/NS/NS[24 h])

(NS/NS/+1.75[27 h])

-6.4,-4.4/-4.8,

-5.2




P. Y. Lee,

I. Peter &

J. Yun

FoxA MASO


NS/NS

(NS/NS[24 h])

(NS/NS[27 h])

NS,+1.9




P. Oliveri,

I. Peter &

J. Yun

Cad MOE17


NS

-5.1/-3.3/-3.8




A. Ransick,

T. Minokawa &

C. Livi

GataC MASO



-1.928




P. Oliveri &

J. Rast

Otx-En12



-6.4




T. Minokawa

Eve MASO

NS

NS/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])

-5.3




A. Ransick &

I. Peter

FoxB MASO




+3.2/+4.1



T. Minokawa

Pmar1 MOE



+5.7




T. Minokawa

Pmar1-En



+4.9




T. Minokawa

Alx1 MASO


-3.2,-2.0/-3.2/

NS/NS/NS

-5.1,-4.7/-3.6/

-1.97/-2.33/

-4.83




P. Oliveri,

Q. Tu &

J. Yun

Ets1 MASO


NS/NS/NS/

NS

-11.5,-10.9/

-4.2/-3.97,-4.71/

-9.81/-3.1/-2.24/

-4.07/-6.87/-4.75




P. Oliveri,

Q. Tu &

J. Yun

Tbr MASO33


-5.3/-2.6/NS/

NS/NS

-4.9,-5.0/-2.7/

-3.64/-2.59/

-3.95




P. Oliveri,

Q. Tu &

J. Yun

Soxb1 MOE26


-2.4,-2.3

-3.2,-3.4




L. Chen

Alx1 MOE



-1.95,-2.68/

NS/NS




P. Oliveri

Ets1 MASO +

Alx1 MOE47



-2.88,-3.62/

-7.5/-4.03




P. Oliveri

Dri MASO


NS/NS/NS

-2.57/-2.86/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/NS/NS

NS/-7.74/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS/NS/NS/NS

(NS/-2.82/

-2.17/NS/-1.84/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Erg MASO


NS/NS/NS/

NS/NS

NS/-4.43/

-3.63/NS/+2.48




Q. Tu,

P. Oliveri &

J. Yun

Bra MASO


NS/NS/NS/

NS

(-2.38/-3.31/

-2.1/-2.88[24 h])

(-1.41/-3.89/

NS/NS[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/-2.02/

-1.67/NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

NS

(-3.7/-1.62/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(NS/-2.84/

-2.64/-2.07[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS

(-4.57/NS/

-1.76[24 h])

(NS/NS/-3.73[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/-2.76/

-1.73

(NS/NS/-2.19[24 h])

(NS/NS/NS[27 h])




I. Peter

OtxHD MASO


-2.96/-2.85/

NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

foxG

Dac MASO


NS/NS/-1.65

(-1.61/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter &

J. Yun

Tgif MASO


NS/NS/NS

(NS/NS/-1.84[24 h])

(NS/NS/NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS

(-2.13/NS/

-2.13[24 h])

(-2.04/NS/

-3.43[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(NS/NS/-1.8[24 h])

(NS/NS/NS[27 h])




I. Peter

OtxHD MASO


NS/-2.92/NS

(-2.7/NS/-2.46[24 h])

(NS/-1.3/-2.08[27 h])




I. Peter

foxN2/3

Ets1 MASO


-1.78/NS/NS/

NS

NS/NS/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/NS/NS

-1.82/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS/NS/NS/NS/

NS

(-1.74/NS/NS/

-1.88/NS/NS/

NS/NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Blimp1b MASO


NS/NS/NS/

NS/NS

(-2.09/NS/

-1.71/NS/NS[24 h])

(NS/-2.95/NS/

-1.42/NS[27 h])




I. Peter &

J. Yun

Otxa MASO


NS/+2.04/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Hox11/13b MASO


NS/NS/NS

(NS/NS/-2.01[24 h])

(-1.62/NS/

-1.75[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/-1.91[24 h])

(NS/-1.94/NS[27 h])




I. Peter

foxO

Hex MASO


NS/NS

-1.91/-3.31




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


NS/NS/NS/

-1.81

NS/NS/-1.87/

-1.92




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS

NS/-2.04/-2.5/

-1.94




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/NS/NS

NS/-1.71/NS




Q. Tu,

P. Oliveri &

J. Yun

Dri MASO


NS/NS/NS

-1.89/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/-1.94/NS/

-1.84/-3.59

NS/-3.62/

-2.95/-2.32/NS




Q. Tu,

P. Oliveri &

J. Yun

foxP

Tgif MASO


NS/NS/NS/

NS

(NS/-1.98/NS/

NS[24 h])

(NS/NS/NS/

-2.23[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

-1.89/NS[24 h])

(-2.04/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Dac MASO


-1.69/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


-2.45/-1.6/NS/

-1.41

(NS/-2.39/NS/

NS[24 h])

(NS/-2.49/NS/

-1.71[27 h])




I. Peter &

J. Yun

GataE MASO


NS/NS/NS/

NS

(NS/NS/-1.64/

NS[24 h])

(-1.74/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/-1.75/NS[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/NS[24 h])

(-1.81/NS/NS[27 h])




I. Peter

fvmo134

DnN MOE7

-1.6

-4.2/-3.5/-2.5/

-2.6





C. Calestani

Gcm MASO



-4.2




A. Ransick

N MASO


-2.2


-1.7 (29 h)

-3.6


C. Calestani

GataE MASO



-3.5/-1.9,-2.1




P. Y. Lee

fvmo234

DnN MOE

NS

-2.5/-2.5





C. Calestani

N MASO


-1.9


-1.8 (29 h)

-2.6


C. Calestani

fvmo334

DnN MOE

-2.6

-2.2/-3.2





C. Calestani

N MASO


-2.4


-2.0 (29 h)

-3.1


C. Calestani

G-cadherin48

Pmar1 MOE



-3.45,NS/

-3.48




S. Wu &

D. McClay

Pmar1 MOE +

Snail MASO



NS,NS/NS




S. Wu &

D. McClay

gatac

Cad MOE31


-2.4/NS

-6.4/-3.6/-4.9




A. Ransick,

T. Minokawa &

C. Livi

Elk-En



-6.0,-5.2,-5.7




M. Arnone

Otx-En21



-2.1/-3.3




A. Ransick &

T. Minokawa

GataE MASO14


NS/NS/NS/

NS/NS/NS/NS/

NS/NS

(+1.69/NS/NS/

NS[24 h])

(NS/+2.17/+2.74/

+2.2[27 h])

-2.2,-2.5/NS,

NS/-2.4,-2.5




P. Y. Lee,

I. Peter &

J. Yun

Dri MASO49


-2.1/-2.3/NS/

NS

-2.87/-2.88/

-2.43

NS/NS



G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

N MASO30


(NS/NS/NS[18 h])

(-2.77[21 h])

-2.6

(-2.77/-2.34/

-3.17/-2.91/-5.4[24 h])

(-2.37/-4.69/

-2.87/-4.11/-2.67[27 h])

NS (29 h)

NS


C. Calestani,

Pei-yun Lee,

I. Peter &

J. Yun

GataC MASO



+3.1,+3.7/NS




P. Oliveri

Hnf6 MASO


-2.5/-3.0/-2.8/

-6.2/-3.1/-3.4


+2.0/+3.0



G. Amore &

O. Otim

Gcm MASO32


-2.2

-2.5




A. Ransick

Soxb1 MOE26



-2.9,-2.9




L. Chen

Gsc MASO37



-3.6/-2.9




G. Amore

MutantSu(H) MOE


NS

-2.7

NS



Pei-yun Lee

FoxA MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])

NS/+2.2


NS/NS


P. Oliveri,

I. Peter &

J. Yun

Ets1 MASO


NS/NS/NS/

NS

NS/-1.81/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/NS

NS/-2.91




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

NS/NS

NS/-3.08/

-2.96/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/-1.78/

-2.47/NS/-1.83[24 h])

(NS/NS/NS/

-2.27/NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(+1.87/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/-3.63/

-2.27

(NS/NS/-1.89[24 h])

(NS/NS/-2.04[27 h])




I. Peter

OtxHD MASO


-4.09/-3.73/

NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

gatae

Cad MOE

NS/NS

-5.1/-3.1

-4.7/-3.6/-3.1




A. Ransick,

T. Minokawa &

C. Livi

DnN MOE


-2.4/NS





C. Calestani

Otx-En


-3.3,-2.2/-2.8,

-3.0/-3.2

NS/NS,-2.4/

-2.4/-4.1/-2.4




A. Ransick &

T. Minokawa

Soxb1 MOE26


-1.6,-3.8

-4.1,-4.2




J. Rast &

K. Young

Soxb1-En



-6.0,-3.5




L. Vega &

W. Chiu

FoxA MASO


NS/NS/NS/

NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])

NS/NS


-2.8,-1.6/-2.5/

-8.5


P. Oliveri,

I. Peter &

J. Yun

Hnf6 MASO




NS/NS/NS/

NS/NS

-2.1/-2.6/-2.7/

NS/NS


G. Amore &

O. Otim

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/-2.72[24 h])

(-2.3/-2.41/

-1.98[27 h])

-2.6




A. Ransick &

I. Peter

Hox11/13b MASO


-1.74/NS/NS

(-1.63/NS/

-2.62[24 h])

(-1.7/-2.16/

-1.7[27 h])

+2.4/+1.7



NS

C. Arenas-Mena &

I. Peter

N MASO


(NS/NS/NS[18 h])

(NS[21 h])

(NS/NS/NS/

NS/NS[24 h])

(NS/NS/NS/

NS/NS[27 h])

-2.84 (37 h)



Pei-yun Lee,

I. Peter &

J. Yun

MutantSu(H) MOE


-2.2/NS/-1.68/

NS/NS/-2.52

NS/NS/NS/

-1.88/NS/NS

NS/NS/NS/

NS/NS/NS



Pei-yun Lee

Dac MASO


NS/-1.51/NS/

-2.73

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Tgif MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

-1.63[27 h])




I. Peter &

J. Yun

Bra MASO


-3.29/-3.11/

NS/-2.02

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


-2.2/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(-1.8/NS/NS/

NS[27 h])




I. Peter &

J. Yun

gcm

Cad MOE

-6.3,-5.1,-5.2/

-3.3

-5.2,-6.1,-4.6/

-4.3

-5.0,-5.7/-5.5




A. Ransick &

T. Minokawa

DnN MOE


-3.5/-2.1,-3.1





C. Calestani

Gcm MASO

-1.9


-2.0/-3.5




A. Ransick

Elk-En



-4.3,-3.0,-6.4




M. Arnone

N MASO


(-5.36/-5.03/

-4.29[18 h])

(-3.68[21 h])

-2.4

(-3.69/-4.28/

-5.75/-4.61/-5.39[24 h])

(-4.09/-4.43/

-3.86/-4.74/-6.32[27 h])

-2.6/

-2.3 (29 h)/-4.93 (37 h)

-2.4


C. Calestani,

Pei-yun Lee,

I. Peter &

J. Yun

FoxA MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])

NS,NS/+3.2/

NS

+2.2,+1.6/+3.2,

+3.0

NS/NS


P. Oliveri,

I. Peter &

J. Yun

Soxb1 MOE26

NS

-3.5,-5.1

-4.1,-3.2




L. Chen

Hnf6 MASO




+2.2/NS



G. Amore &

O. Otim

MutantSu(H) MOE


-2.6/-4.0

-3.3/---

-3.4/-4.0



Pei-yun Lee

Tgif MASO


NS/NS/NS/

NS/NS/NS/NS/

NS

(NS/NS/NS/

-1.72/NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Blimp1b MASO


NS/-3.2/NS/

NS/NS

(NS/-1.6/NS/

NS/-3.93[24 h])

(NS/NS/NS/

-1.86/-3.73[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(NS/NS/-3.9[24 h])

(NS/NS/-2.05[27 h])




I. Peter

Eve MASO

NS/-3.65

NS/NS

(NS/NS/NS[24 h])

(-2.23/NS/NS[27 h])




I. Peter

gsc

Dri MASO

-5.0/-7.0

-7.0/-8.6/-4.0/

-2.9/NS/-1.88/

-1.7

-3.23/-3.96/

-2.15

-2.6/-4.5



G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

Dri-En


-3.6/-2.7





G. Amore

Alx1 MASO


-3.6,-2.5/NS/

NS/NS/NS/

NS

NS/NS/NS/

NS/NS




P. Oliveri,

Q. Tu &

J. Yun

Soxb1 MOE26


-4.0,-9.1

-6.7,-4.8




L. Chen

Soxb1-En



-3.3,-1.9




L. Vega &

W. Chiu

Pmar1 MOE



-13.3




P. Oliveri &

L. Vega

Cad MOE



-6.5




P. Oliveri &

L. Vega

Pmar1-En



-6.6




P. Oliveri &

L. Vega

Hnf6 MASO


-6.1/-4.9/-6.0





G. Amore &

O. Otim

GataE MASO45



-5.0,-4.8/-4.0,

-4.1




P. Y. Lee

Tel MASO


NS/NS/-1.95

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/NS/NS

NS/-2.15/NS




Q. Tu,

P. Oliveri &

J. Yun

Tbr MASO


-1.64/NS

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

SoxC MASO


-9.71/NS

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO49


NS/NS/-2.88/

NS

-3.0/-2.79/

-3.19/-3.25




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO49


NS/NS/-2.71/

-2.02

-2.48/-3.1/NS/

-8.93




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO49


-2.68/NS/

-2.78/-2.01/-2.46

NS/-2.98/

-2.41/-1.76/NS




Q. Tu,

P. Oliveri &

J. Yun

hex

Ets1 MASO


-4.02/-5.21/

-2.61/-3.8

NS/-1.86/

-3.39/-1.99




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/-1.86

NS/-1.88/

-2.19




Q. Tu,

P. Oliveri &

J. Yun

Dri MASO


NS/NS/NS

-1.77/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


-1.65/-2.1

NS/-3.85




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-1.63/NS/

-4.19/-1.71/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

hh

FoxA MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(-4.52/-8.1/-6.0/

-3.09[27 h])

-2.5/-2.3

-3.3/-2.7


P. Oliveri,

I. Peter &

J. Yun

Tgif MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/-1.72/

-2.15/-2.01[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

NS/NS[24 h])

(-4.7/NS/-3.0/

-1.45/NS[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(-2.06/-8.5/NS/

-1.67[27 h])




I. Peter &

J. Yun

GataE MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(-3.8/-2.19/

-5.02/-3.54[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/-5.76/

-1.87/-3.21[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(-2.53/NS/NS/

-2.67[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/-2.2/-3.44/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(NS/NS/NS[24 h])

(-3.74/-2.91/

NS[27 h])




I. Peter

Otxa MASO


NS/NS

(NS/-1.67[24 h])

(NS/NS/NS[27 h])




I. Peter

Eve MASO

NS

NS/NS

(NS/-1.96[24 h])

(NS/-3.25/NS[27 h])




I. Peter

OtxHD MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/-3.53/

-3.75[27 h])




I. Peter

hnf1

GataE MASO


-2.03/-2.48/

NS/-3.74

(NS/NS/-3.47/

-2.29[24 h])

(-3.48/NS/

-3.44/NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/-3.42/NS/

-2.74

(-2.1/-2.5/

-1.54/-2.37[24 h])

(-3.7/-1.85/

-2.08/NS[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

-1.97

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Tgif MASO


-2.11/NS/NS/

-2.26

(NS/NS/NS/

-1.65[24 h])

(NS/NS/NS/

-2.09[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/-2.34/

-2.89

(-1.41/NS/

-2.92/NS[24 h])

(-2.21/NS/NS/

NS[27 h])




I. Peter &

J. Yun

N MASO


+1.69/NS/NS

(+2.63/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Dac MASO


-2.5/NS/-3.28/

NS

(NS/NS/-2.5/

NS[24 h])

(NS/NS/-1.91/

NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


-3.86/-2.11/

NS/NS/NS

(NS/-1.95/-1.5/

NS/NS[24 h])

(-1.81/-2.74/

NS/-1.63/NS[27 h])




I. Peter &

J. Yun

Otxa MASO


-3.68/NS/-3.4

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Hox11/13b MASO


NS/NS/NS

(-1.63/NS/

-2.43[24 h])

(-2.28/-1.97/

-1.72[27 h])




I. Peter

Eve MASO

NS/NS

-2.98/-3.81/

NS

(-2.44/-1.96/

-3.34[24 h])

(-3.19/-3.05/

-2.26[27 h])




I. Peter

OtxHD MASO


NS/-2.25/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Hnf1 MASO



(NS/NS/NS[24 h])

(NS/+1.45/+1.93[27 h])




I. Peter

hnf6

Tbr MASO


NS/NS

NS,+1.9/NS/

NS




P. Oliveri,

K. Young,

Q. Tu &

J. Yun

Tgif MASO49


NS/NS/NS/

NS/NS

(NS/-2.67/

-2.19/-1.95/NS[24 h])

(NS/-1.7[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Ets1 MASO


NS/NS/NS/

NS

NS/NS/-2.09/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/NS

-1.85/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

-3.46/-1.66

NS/-1.81/

-1.76/-1.93/NS




Q. Tu,

P. Oliveri &

J. Yun

Dac MASO


+1.68/NS

(NS/NS[24 h])

(NS/NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/-2.22

(NS/NS[24 h])

(NS/NS[27 h])




I. Peter &

J. Yun

Otxa MASO


+2.4/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Eve MASO

NS

NS/+1.6

(NS/NS/-1.87[24 h])

(-2.93/-2.5/NS[27 h])




I. Peter

Hnf1 MASO



(NS/NS/NS[24 h])

(NS/NS/+1.61[27 h])




I. Peter

hox11/13b

Blimp1b-En

-7.6

-6.2

-3.2




C. Livi

Cad MOE

-5.4

-5.6/-2.7

-5.2/-3.1




A. Ransick &

T. Minokawa

Otx-En


-4.8/-4.3/-6.5

-3.0/-4.3/-6.6/

-8.8




A. Ransick &

T. Minokawa

Soxb1 MOE26

-2.4,-2.3

-1.8,NS

NS,NS/NS




L. Chen

Eve MASO

NS/NS/NS

-1.8/-1.8/NS/

NS/NS

(-1.89/-1.62/

-2.48[24 h])

(-1.95/-2.0/

-2.04[27 h])

-2.8/-2.1




A. Ransick,

C. Livi &

I. Peter

GataE MASO


NS/NS/NS

(+1.79/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

+2.17[27 h])




I. Peter &

J. Yun

N MASO


NS/+1.77/NS

(NS/-1.77/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(+1.62/+1.52/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/+1.42/

+1.98[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

NS

(NS/NS/+1.77/

+1.98[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(+2.31/+2.82/NS[24 h])

(+2.38/+2.59/+1.22[27 h])




I. Peter

hsp70

Hox11/13b MASO



NS/+1.6




C. Arenas-Mena

jun

Dri MASO


NS/+1.66/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

-5.32/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

krl

Cad MOE

-9.9,-10.8


-4.9




P. Oliveri &

K. Young

Pmar1 MOE

NS,NS


-2.1,-2.5




P. Oliveri &

K. Young

Pmar1-En

NS,NS


NS,NS




P. Oliveri &

K. Young

Pmar1 MOE +

Cad MOE

-6.3,-7.4


-2.5




P. Oliveri &

K. Young

Pmar1-En +

Cad MOE

-6.1,-5.2


NS




P. Oliveri &

K. Young

Hnf6 MASO


NS/-2.1/NS/

-1.9/NS


+2.9/+3.5/+2.0/

+3.4/+5.2



G. Amore &

O. Otim

Soxb1 MOE26

-2.9,-2.9

-3.8,-4.0

-3.3,-3.1/NS




L. Chen

Tbr MASO


NS/NS

+2.66/NS




Q. Tu,

P. Oliveri &

J. Yun

Dri MASO


NS/NS/NS

NS/+1.97/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS/NS/NS/NS

(+2.54/NS/NS/

NS/NS/NS/NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Alx1 MASO


NS/NS/NS

+2.21/+1.81/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

NS/NS

+2.41/NS/NS/

NS/+2.36




Q. Tu,

P. Oliveri &

J. Yun

GataE MASO


NS/NS/NS/

NS

(NS/+2.46/+2.85/

+1.68[24 h])

(+4.58/+2.82/+2.9/

+1.43[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/-1.65/NS/

NS/NS

(NS/NS/NS/

NS/+2.01[24 h])

(+1.82/+2.64/+1.6/

+2.0/NS[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/+1.48/+2.97/

+1.79[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

NS

(NS/NS/+1.94/

NS[24 h])

(NS/+1.82/+3.03/

+3.01[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/+2.03/NS/

+2.46[27 h])




I. Peter &

J. Yun

N MASO


NS/NS/NS

(-2.51/-1.65/

NS/NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

FoxA MASO


NS/NS/NS/

NS

(NS/+1.6/NS/

NS[24 h])

(+2.15/+1.56/+1.94/

NS[27 h])




I. Peter &

J. Yun

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/NS[24 h])

(-1.77/NS/NS[27 h])




I. Peter

Hox11/13b MASO


NS/NS/NS

(-1.71/NS/

-1.79[24 h])

(NS/NS/-1.64[27 h])




I. Peter

Otxa MASO


NS/NS/NS

(NS/+1.77/NS[24 h])

(NS/NS/+2.54[27 h])




I. Peter

lim1

GataE MASO


-1.6/-2.3,-1.9/

NS,NS/NS,

NS

-2.6,-2.2/-2.3,

-2.3




P. Y. Lee

Cad MOE

NS

-2.5/NS

-5.0/NS




A. Ransick &

T. Minokawa

Elk-En6



-6.3,-3.7,-6.5




M. Arnone

Soxb1 MASO26

-2.9


-2.3

NS



C. Livi

Otx-En


-2.5/NS

-3.3/-5.4




A. Ransick &

T. Minokawa

msp130

Dri MASO


-3.6/-5.1/-2.1/

-2.4/-2.0/-2.5/

-3.0/NS/-1.95/

NS

NS/NS/NS




G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

Cad MOE19



-5.3




C. Livi

Dri-En


-3.6/-1.9





G. Amore

Pmar1 MASO

+3.1


+6.4




P. Oliveri

Pmar1-En

+1.6


+4.7




P. Oliveri

Krl MASO26

-2.423,-2.123/

-4.8,-3.3/-4.9,

-2.8

-2.2/-1.7,-2.7/

NS

-1.9,-2.7/NS




J. Rast &

K. Young

Hnf6 MASO


-2.8/-2.2/-2.7/

-3.0/-3.4/NS/

-1.8



NS/NS


O. Otim &

G. Amore

FoxB MASO



-1.7

-2.0



T. Minokawa

Ets1 MASO


-3.3/-4.3/NS/

-5.63/-8.84/

-5.66/-3.42/-6.02

-4.3/-5.05/

-2.48/-5.42/-4.58/

-6.4/-4.81




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Alx1 MASO43


-2.9,-3.1/-2.4/

NS/-3.73/

-2.41/-4.09

-1.8/-2.1/

-3.07/-2.33/-4.49




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Gsc MASO38


-3.2,NS

-2.2/-3.7




G. Amore

Soxb1 MOE26



-8.4,-8.9/-2.8,

-1.6




L. Chen

Alx1 MOE


NS/NS

NS/NS




P. Oliveri

Ets1 MASO +

Alx1 MOE47


NS/-3.91

-3.23/-4.54




P. Oliveri

Hex MASO


-4.08/-1.57/

-3.33

-2.0/NS/-4.88




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


-2.87/-1.84/

-2.62

NS/-2.92/

-2.57




Q. Tu,

P. Oliveri &

J. Yun

Tbr MASO


NS/NS

-1.73/NS




Q. Tu,

P. Oliveri &

J. Yun

SoxC MASO


-2.02/NS

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-4.86/-2.0/

-6.21/-3.07/-2.52

NS/-3.25/

-2.79/-1.61/NS




Q. Tu,

P. Oliveri &

J. Yun

msp130-like

Bra MASO1



-4.3




J. Rast

Pmar1 MOE

+3.2


+5.8




P. Oliveri

Pmar1-En

+2.4


+4.9




P. Oliveri

Alx1 MASO


-4.7/-3.1/-3.5/

NS

NS/NS




P. Oliveri

Ets1 MASO


-2.3/-5.58,

-5.29/-2.08

-2.8/-5.42,

-5.6/-13.23/-3.47




P. Oliveri

Alx1 MOE


-2.29,-1.99/

NS

-2.38,-2.55/

NS/NS




P. Oliveri

Ets1 MASO +

Alx1 MOE47


-6.35,-6.06/

-2.52

-5.72,-5.89/

-5.77/-3.99




P. Oliveri

Hex MASO


-3.05/-1.67

NS/-4.14




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


-8.56/-8.38/

-3.29/-6.36

-6.39/-5.15/

-7.49/-7.91




Q. Tu,

P. Oliveri &

J. Yun

Alx1 MASO


-4.4/-2.83/

-3.95

-2.83/-2.11/

-4.65




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


-2.06/-1.69/

NS/-1.85

-1.6/-2.21/

-2.07/-1.72




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-2.07/NS/-2.6/

-2.06/-2.2

NS/-1.61/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

msx

GataE MASO


NS/NS/NS/

NS

(NS/NS/-3.51/

-2.45[24 h])

(-3.32/NS/

-3.69/NS[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(-3.09/NS/

-3.21/-1.69[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

N MASO


NS/NS/NS

(+3.12/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

NS

(-1.53/-3.04/

-1.79/NS[24 h])

(NS/-2.0/NS/

-1.62[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/-1.95/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Otxa MASO


-1.94

(NS[24 h])

(NS[27 h])




I. Peter

myc

Myc MASO


+1.6/NS/+1.95/

NS

(+1.56/+1.52/NS/

+1.71[24 h])

(NS/+1.71/+2.09/

+1.69[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

NS/NS[24 h])

(-2.05/NS/NS/

NS/NS[27 h])




I. Peter &

J. Yun

GataE MASO


-1.48/NS/

-1.84/NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/NS/-1.75[27 h])




I. Peter

not

GataE MASO


-1.9,NS/NS/

NS,NS

-2.2,-2.1/-2.4,

-2.3




P. Y. Lee

Otx-En

-3.6

-5.0

-2.1/-3.3




A. Ransick &

T. Minokawa

GataC MASO



-1.7/NS




P. Oliveri &

J. Rast

Tgif MASO49


NS/NS/NS

-3.32/-2.16/

-1.97




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


NS/NS/NS/

NS

NS/NS/-2.87/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/+1.74

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

NS/NS

NS/NS/-1.72/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

notch

GataE MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/NS/-1.79/

-1.53[27 h])




I. Peter &

J. Yun

N MASO


+1.87/NS/+1.49

(NS/NS/+2.49/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(NS/NS/NS[24 h])

(NS/NS/-1.64[27 h])




I. Peter

Otxa MASO


NS/+1.86/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

nrl

GataE MASO


+2.3,NS/+1.8,

+2.7

+2.1,+1.6,NS/

+2.3,+1.8




P. Y. Lee

Bra MASO1



+2.4,+4.3




J. Rast

Otx-En3


NS

+3.5




A. Ransick &

T. Minokawa

Tbr MASO


-2.2,-3.4,-3.4,

-2.7/-1.8/-2.4/NS/

NS/NS

NS/NS/+2.31/

NS/NS




P. Oliveri,

Q. Tu &

J. Yun

Alx1 MASO


-1.8/-2.7/NS/

NS

NS/NS/NS/

NS




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Pmar1 MOE

+2.4


+4.5




P. Oliveri &

L. Vega

Cad MOE

+3.6


+2.6




P. Oliveri &

L. Vega

Pmar1-En

+3.4


+2.3




P. Oliveri &

L. Vega

FoxN2/3 MASO


NS/-2.25/

-2.01

NS/+1.91/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/-1.7/-1.82/

+1.78

+1.57/+3.92/NS/

+3.83




Q. Tu,

P. Oliveri &

J. Yun

Tel MASO


NS/NS/-2.31

+1.75/+1.6/NS




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


NS/+2.13/NS

+1.77/+3.66/NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/NS/NS

NS/NS/+2.28




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/-2.4/NS/

-2.09/-2.54

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

otx3

Blimp1b MASO

-3.8,-3.0

-1.8,-2.1,-2.3,

-2.3





C. Livi

otxb1/2

Blimp1b MASO

-2.7,-2.1

-2.1,-1.9/NS/

NS/-1.73/NS/

NS/NS

(NS/NS/NS/

NS/-1.67[24 h])

(-2.12/NS/NS/

NS/NS[27 h])

-2.3/-2.7




C. Livi,

I. Peter &

J. Yun

Blimp1b-En

-5.6

-4.6

-3.6




C. Livi

GataE MASO


-2.5,-3.1/-3.6,

-3.6/-1.86/NS/NS/

NS

(-1.41/-1.74/

-1.91/-1.49[24 h])

(-1.65/-2.64/

NS/-1.72[27 h])

-1.8,NS,NS/

-3.0,-3.7




P. Y. Lee,

I. Peter &

J. Yun

Cad MOE

NS

+10.3/+1.7

NS/NS




A. Ransick &

T. Minokawa

Otx-En

-3.8/-3.7

-3.2/-4.1/-3.3

-2.1/-2.3/-3.2/

-3.8




A. Ransick &

T. Minokawa

Tgif MASO


NS/NS/NS/

NS

(NS/NS/-1.9/

-1.63[24 h])

(NS/-1.49/NS/

-1.81[27 h])




I. Peter &

J. Yun

Dac MASO


NS/NS/NS/

NS

(-2.13/NS/NS/

-2.47[24 h])

(-1.92/NS/

-1.64/NS[27 h])




I. Peter &

J. Yun

N MASO


NS/+2.02/NS

(NS/+3.55/NS/

NS[24 h])

(+2.08/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/-3.05/

-2.41/-1.82

(NS/-1.68/NS/

NS[24 h])

(-1.77/-1.48/

NS/-2.07[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(-1.63/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Otxa MASO


NS/NS/+2.05

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

pks

GataE MASO


-2.2/-3.2/-1.9

-3.4,-1.6,NS/

-3.2,-3.6




P. Y. Lee

Bra MASO1



-2.6




J. Rast

DnN MOE7

-1.8

-3.3,-2.5/-2.7,

-3.1





C. Calestani

Elk-En7



-7.1,-5.2,-6.5




I. Arone

Gcm MASO


-6.1/-7.2

-5.2/-3.3/

-12.3/-7.8




A. Ransick

N MASO


-2.6


-3.4 (29 h)

-3.1


C. Calestani

DnN MOE




-2.1 (29 h)



C. Calestani

Krl MASO


NS/NS

-2.1,-1.7




L. Chen

FoxA MASO



+3.7


NS/NS


P. Oliveri

Hex MASO49


-3.63/-2.14

NS/-4.69




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/-2.54/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

SoxC MASO


-2.61/NS

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS

NS/NS/-1.81/

NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO49


-4.86/NS/

-7.53/-2.85/-2.29

NS/-2.61/

-2.18/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

pm27/sm27

Dri MASO

-3.2/-5.0

-4.0/-4.3/-2.3/

-2.8





G. Amore

Dri-En


-3.2/-2.3





G. Amore

Pmar1 MOE

NS


+4.0




P. Oliveri

Pmar1-En

NS


+2.7




P. Oliveri

Gsc MASO38


-2.2/-3.3

-2.0/-3.0




G. Amore

Hnf6 MASO


-5.8/-4.0/-3.5/

-5.1/-5.3/-2.6/

-4.0



NS


G. Amore &

O. Otim

Soxb1 MOE26



-7.8,-13.2/

-2.5




L. Chen

Ets1 MASO



-4.4/NS/-3.21,

-5.18/-6.55




P. Oliveri &

L. Vega

Alx1 MOE



NS,-3.56/NS




P. Oliveri

Ets1 MASO +

Alx1 MOE47



-4.22,-6.18/

-3.33




P. Oliveri

Hex MASO


-2.52/NS/

-2.44

NS/NS/-4.78




Q. Tu,

P. Oliveri &

J. Yun

Tel MASO


-2.82/-3.51/

NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


-2.53/-3.27/

-3.13/-4.36

-3.48/-4.74/

-7.7/-4.72




Q. Tu,

P. Oliveri &

J. Yun

Alx1 MASO


-4.02/-1.98/

-1.93

-1.97/-1.6/

-4.22




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


-2.03/-2.37/

NS/NS

-2.53/-1.91/

-2.58/-2.24




Q. Tu,

P. Oliveri &

J. Yun

Dri MASO


-1.66/NS

-2.32/-2.09/

NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-3.49/-4.64/

-8.2/-3.98/-4.08

-2.02/-4.53/

-3.88/-2.54/NS




Q. Tu,

P. Oliveri &

J. Yun

pmar1

Cad MOE

-4.0 (6 h)/

-3.0 (6 h)






A. Ransick &

T. Minokawa

Otx-En

-3.1,-2.9/-2.8






A. Ransick &

T. Minokawa

six1/2

Gcm MASO



-2.07/-1.68/

-2.23




S. Materna

sm30

Dri MASO


-6.2/-5.4/-5.6/

-5.6


-7.5/-5.0/-6.0



G. Amore

Dri-En




-6.2/-5.4/-5.6/

-5.6



G. Amore

Tbr MASO



-1.8




P. Oliveri &

L. Vega

Alx1 MASO



-2.5




P. Oliveri &

L. Vega

Hnf6 MASO35, 40




-3.2/NS/-2.1/

-5.5/-4.1/-3.2/

-4.0

-4.5/-6.0/-3.6/

-2.7/-4.5


G. Amore &

O. Otim

Ets1 MASO



NS/NS




P. Oliveri

Alx1 MOE



+2.57/+2.34




P. Oliveri

Ets1 MASO +

Alx1 MOE



NS/NS




P. Oliveri

sm50

Dri MASO22

NS/-3.0/-2.1/

-4.8

NS/-2.5/-4.0/

-4.8/-3.2/-2.2/

-2.54/-2.61

-2.64/-2.46/

NS

-4.0/-3.0/NS/

-2.5

+4.0/+3.4


G. Amore,

Q. Tu,

P. Oliveri &

J. Yun

Dri-En22


-3.2/-2.3





G. Amore

Bra MASO1



-2.2




J. Rast

Pmar1 MOE1



+4.4/+2.3




P. Oliveri

Pmar1-En11



+2.5/NS




P. Oliveri

Eve MASO



-3.8,-3.5




A. Ransick

Gsc MASO2, 38


NS,NS,-1.7

-3.2/-2.0

NS/-3.0,-3.0



G. Amore

Hnf6 MASO


-2.3/-2.5/-2.8/

-3.4/-2.5/-2.4/

NS


NS/NS

NS


O. Otim &

G. Amore

Krl MASO26

-3.0,NS/-5.3,

-4.2

-3.2/NS,-2.4

-4.1,-4.9/-1.7




K. Young &

J. Rast

Ets1 MASO


-1.9/-1.9,

-2.01/-2.2/-3.04/

NS/NS/-1.92/

-4.92

-6.5/-4.6/

-3.44,-5.29/-4.25/

-4.98/-4.31/-4.16/

-6.79/-3.83




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Alx1 MASO


-2.7,NS/NS/

-2.88/NS/NS

-3.4/-2.0/NS/

-2.09/NS/

-4.51




P. Oliveri,

L. Vega,

Q. Tu &

J. Yun

Eve MASO



-3.5




A. Ransick

Soxb1 MOE26



-4.5,-9.9/-3.0,

-1.8




L. Chen

Alx1 MOE


NS,NS/NS/

NS

NS,-2.04/NS/

-2.59




P. Oliveri

Ets1 MASO +

Alx1 MOE47


-2.37,-2.49/

-2.38/-2.46

-3.98,-5.83/

-5.01/-7.38




P. Oliveri

Hex MASO


-2.07/NS/

-2.23

-1.59/NS/

-4.43




Q. Tu,

P. Oliveri &

J. Yun

Tel MASO


-3.82/-1.96

-2.25/-1.81




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS

-2.03/-3.12/

-2.13




Q. Tu,

P. Oliveri &

J. Yun

Tbr MASO


NS/NS

NS/-1.79




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-3.29/-3.89/

-2.1/-3.77/-4.0

-2.04/-5.18/

-4.34/-2.62/NS




Q. Tu,

P. Oliveri &

J. Yun

Snail

Pmar1 MOE48



+2.99/NS,

+2.03




S. Wu &

D. McClay

Alx MASO48



-2.54/-3.4,NS




S. Wu &

D. McClay

DN-Ets MOE48



NS




S. Wu &

D. McClay

Hex MASO


NS/NS

-2.22/-6.18




Q. Tu,

P. Oliveri &

J. Yun

Dri MASO49


NS/NS/NS

-2.91/-5.65/

-3.21




Q. Tu,

P. Oliveri &

J. Yun

Tel MASO


NS/NS/NS

-6.17/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tbr MASO


NS/NS

NS/-8.57




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


NS/NS/NS/

NS

NS/-3.06/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS

NS/-2.36/NS/

-2.05




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

NS/NS

NS/-3.22/

-5.74/NS/+2.19




Q. Tu,

P. Oliveri &

J. Yun

soxb1

Soxb1 MASO26

NS,NS/NS,

NS/NS/+2.5/NS/

+3.0,NS/NS,+2.0/

NS (6 h)


+3.0,+3.4/+3.6,

+3.3

+4.3,+4.3/+3.8,

+3.9



C. Livi,

J. Rast &

K. Young

Cad MOE



NS




P. Oliveri &

K. Young

Pmar1 MOE



-7.0




P. Oliveri &

K. Young

Pmar1-En



-4.4




P. Oliveri &

K. Young

Pmar1 MOE +

Cad MOE



-5.9




P. Oliveri &

K. Young

Pmar1-En +

Cad MOE



-4.2




P. Oliveri &

K. Young

Tgif MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

-1.63[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/+3.47/

NS/NS

(NS/NS/NS/

NS/NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Krl MASO


+1.73/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

soxC

SoxC MASO


+1.8/+1.89/NS/

+1.97/NS

(NS/NS/+1.49/

+1.53/+1.61[24 h])

(+1.7/NS/NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Ets1 MASO


-1.84/NS/NS/

NS

NS/NS/-1.69/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/+1.7/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/NS/NS/

NS/NS[24 h])

(NS/-1.93/NS/

NS/NS[27 h])




I. Peter &

J. Yun

sutx

DnN MOE

NS


-2.7/-2.6/-2.9




C. Calestani

Gcm MASO


-4.3

-6.7




A. Ransick

N MASO


-3.1


NS

-4.6


C. Calestani

Krl MASO


NS/NS

-1.7,NS,-3.2,

-2.7




L. Chen

GataE MASO



-4.2/-1.9/-1.6




P. Y. Lee

tbr

Bra MASO11



-1.8




J. Rast

Pmar1 MOE

+2.0/NS


+5.9/+3.4




P. Oliveri

Pmar1-En

+1.7/NS


+4.7/+2.6




P. Oliveri

Tbr MASO


NS/NS/NS

NS/+1.76/+1.66




Q. Tu,

P. Oliveri &

J. Yun

tel

Tel MASO


+2.31/+3.78/+2.82

+2.63/+2.25/+2.93




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/+2.12/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


-1.65/NS/NS/

NS

NS/NS/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Hex MASO


NS/+1.89/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


+1.93/NS/+2.06/

NS/NS

NS/NS/NS/

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

tgif

Hex MASO


-2.28/-3.53/

-2.85

NS/NS/-4.08




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


-1.67/-1.82/

NS/-2.7

-2.0/-1.59/

-2.51/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


-2.49/-1.93/

-1.96/-1.41/NS/NS/

-2.06

(-1.86/-3.07/

NS/-1.88/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Tel MASO


NS/-2.39

NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Tbr MASO


-2.24/NS/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

SoxC MASO


-1.71/NS/NS/

NS/NS

(NS/NS/NS/

NS/NS[24 h])

(NS/NS/NS[27 h])




Q. Tu,

P. Oliveri,

J. Yun &

I. Peter

Dri MASO


NS/-2.33/NS

NS/-1.76/NS




Q. Tu,

P. Oliveri &

J. Yun

Alx1 MASO


-2.33/NS/NS

NS/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


-3.36/-2.87/

-2.13/-2.82/-3.08

NS/-3.73/

-2.09/-2.21/NS




Q. Tu,

P. Oliveri &

J. Yun

GataE MASO


NS/NS/NS/

-2.31

(NS/NS/NS/

NS[24 h])

(-1.74/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


-1.53/-3.85/

-1.53/-3.21

(-2.04/-3.43/

-2.37/-2.31[24 h])

(-3.15/-1.64/

-1.55/-1.67[27 h])




I. Peter &

J. Yun

Krl MASO


NS/-2.05/

-3.43/-4.12

(-1.62/NS/NS/

-1.57[24 h])

(NS/NS/NS/

-1.94[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(-1.75/-2.65/

-1.63/NS[24 h])

(-1.79/-2.05/

NS/-1.56[27 h])




I. Peter &

J. Yun

Dac MASO


-2.05/-1.45/

NS/NS

(-2.79/NS/-2.0/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


-4.58/-1.41/

NS/-3.61/-3.0

(-2.62/NS/

-2.05/NS/-2.41[24 h])

(-2.54/-2.49/

NS/-1.81/NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/NS

(-2.07/NS/

-1.68[24 h])

(-2.06/NS/

-1.92[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/NS[24 h])

(-1.88/-2.02/

NS[27 h])




I. Peter

OtxHD MASO


-1.67/NS/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

ui (via endo16)

Cad MOE9

-2.9

-6.2

-5.2




A. Ransick &

T. Minokawa

GataE MASO

-2.8,-3.5/-2.7,

-1.8






P. Y. Lee

unc4.1

Tgif MASO50


NS/NS/NS/

NS

(NS/-1.86/

-1.87/-1.47[24 h])

(NS/NS/NS/

-2.25[27 h])




I. Peter &

J. Yun

GataE MASO


NS/NS/NS/

NS

(NS/NS/-3.67/

-2.47[24 h])

(-3.04/NS/

-4.41/NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


NS/NS/NS/

NS/NS

(NS/-1.41/NS/

-2.16/-2.05[24 h])

(-3.28/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Krl MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/-1.46/NS/

-2.77[27 h])




I. Peter &

J. Yun

Dac MASO50


NS/NS/NS/

NS

(-3.72/-1.83/

-3.36/-2.46[24 h])

(NS/-1.53/

-1.47/-1.94[27 h])




I. Peter &

J. Yun

N MASO


NS/NS/NS

(+2.68/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Bra MASO


NS/NS/NS/

NS

(-2.09/-2.96/

-2.79/NS[24 h])

(NS/-4.95/

-1.49/-1.68[27 h])




I. Peter &

J. Yun

Myc MASO


NS/NS/NS/

NS

(-1.58/-2.32/

-1.83/NS[24 h])

(NS/-2.07/NS/

NS[27 h])




I. Peter &

J. Yun

Hox11/13b MASO


NS/NS/-2.33

(NS/NS/-4.06[24 h])

(NS/NS/-1.82[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(-1.93/-2.66/

-3.91[24 h])

(-2.73/-2.47/

-2.53[27 h])




I. Peter

vegfrII

Hex MASO


NS/NS

NS/-4.03




Q. Tu,

P. Oliveri &

J. Yun

Ets1 MASO


NS/NS/NS/

NS

-3.66/-2.49/

-3.8/-2.4




Q. Tu,

P. Oliveri &

J. Yun

Dri MASO


NS/NS/NS

-1.62/-2.2/NS




Q. Tu,

P. Oliveri &

J. Yun

Alx1 MASO


-2.56

-2.48

NS



P. Oliveri &

Q. Tu

Alx1 MASO


NS/NS

NS/-2.87




Q. Tu,

P. Oliveri &

J. Yun

FoxN2/3 MASO


NS/NS/NS

NS/-1.84/NS




Q. Tu,

P. Oliveri &

J. Yun

Tgif MASO


NS/NS/NS/

NS

NS/NS/NS/

-2.51




Q. Tu,

P. Oliveri &

J. Yun

Erg MASO


NS/NS/NS/

NS/NS

NS/-2.89/

-2.48/NS/NS




Q. Tu,

P. Oliveri &

J. Yun

wnt8

Blimp1b MASO

NS/NS

-1.6/NS

(NS[24 h])

(NS[27 h])

NS




C. Livi,

I. Peter &

J. Yun

Blimp1b-En

-4.2 (6 h),

-2.0/-3.7

-3.2

NS




C. Livi

Cad MOE

-4.5 (6 h)/

-5.4/-5.3/-11.5

-3.9/-2.8

-5.3/-5.0/-4.9




A. Ransick,

P. Oliveri &

L. Vega

Otx-En

NS/NS

+2.6/+7.7/+2.1

NS/NS/NS




A. Ransick &

T. Minokawa

GataE MASO15


NS/+2.3/NS/

NS/NS

(NS/NS[24 h])

(NS/NS[27 h])

NS,NS/NS,

NS/NS,NS




P. Y. Lee,

I. Peter &

J. Yun

Soxb1 MOE26

-2.3,-2.8

-2.3,-2.6

NS,-2.3/NS




L. Chen

Pmar1 MOE

+2.3


-4.1




P. Oliveri &

L. Vega

Pmar1-En



-2.6




P. Oliveri &

L. Vega

Bra MASO


-2.01/NS/+1.76/

NS

(NS/NS/NS/

NS[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Otxa MASO


NS/+1.71/NS

(NS/NS/NS[24 h])

(NS/NS/NS[27 h])




I. Peter

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/-1.66[24 h])

(NS/-2.36/NS[27 h])




I. Peter

z166

Gcm MASO



-2.01/-1.75/

-2.07/-1.58




S. Materna

z188

GataE MASO


NS/NS/NS/

NS

(NS/NS/NS/

NS[24 h])

(NS/-1.68/NS/

NS[27 h])




I. Peter &

J. Yun

Blimp1b MASO


-1.83/NS/NS/

NS/NS

(-2.22/NS/NS/

NS/NS[24 h])

(NS/-2.09/

-1.49/-2.09/NS[27 h])




I. Peter &

J. Yun

N MASO


NS/NS/NS

(NS/NS/NS/

+1.68[24 h])

(NS/NS/NS/

NS[27 h])




I. Peter &

J. Yun

Eve MASO

NS/NS

NS/NS/NS

(NS/NS/-1.77[24 h])

(-1.71/NS/NS[27 h])




I. Peter

z48

Tgif MASO


NS/NS/NS/

NS

NS/+1.71/NS/

NS




Q. Tu,

P. Oliveri &

J. Yun

Note: Smaller effects are shown as "NS", except where individual NS data are included together with other significant measurements to display scatter or inconsistencies amongst different batches of cDNA. Commas separate replicate measurements in the same cDNA batch; slashes indicate different batches of cDNA from independent experiments, dashes indicate a missing data point

Perturbation:

Genes not affected or shown to be affected only indirectly (0 to 24h, unless otherwise noted)

Alx1 MASO

L1 (18, 24, 30 h), cyclophillin, delta, endo16, ets1, eve, gatac, gcm, pmar1, sm/pm27, snail, tbr, [erg, foxA, foxN2/3, foxO, hex, hnf6, jun, not, pks, soxC, tel, z48 (18-24 h)]

Blimp1b MASO

bra, hox11/13b, lim1, [dac, delta, hesC, msx, notch (18-27 h)]

Blimp1b-En

dec, dpt, endo16, foxa, gatae, gcm, not, nrl, otx a, pks, pmar1, soxb1, tbr

Bra MASO

capk, dec, delta, dpt, ephx, ficolin, msp130-like, nrl, pks, sm50, tbr, [blimp1b, dac, eve, foxN2/3, gcm, hesC, myc, notch, soxB1, soxC, z188 (18-27 h)]

Brn1/2/4 MASO

[Brn1/2/4, otxb1/2 (18, 30, 45 h)], [gatae, hox11/13b (45 h)]

Cad MOE

dec, elk, endo16, foxc, hnf6, nrl, soxb1, tbr, z12-1

Dac MASO

[blimp1b, bra, delta, eve, foxN2/3, gataC, gcm, hesC, myc, notch, soxB1, soxC, wnt8, z188 (18-27 h)]

DnN MOE

blimp1, bra, capk, dec, delta, e(spl)-1, elk, endo16, eve, foxa, foxb, gatac, hmx, hox11/13b, not, notch, nrl, otx b1/2, su(h), tbr, wnt8

Dri MASO

N, bra, delta, dri (in pmc's), e(s), ets1, eve, foxa, gatae, gcm, hnf6, hox11/13b, lim1, pmar1, tbr, wnt8, z12-1, [elk, otx a, su(h) (16-20 h)], [alx1, erg, foxN2/3, msp130L, pks, soxC, tel, z48 (18-24 h)], [not, nrl (16-24 h)]

Dri-En

delta, dri (in pmc's), ets1, hnf6, pmar1, tbr, z12-1 (16-20 h)

Elk-En

delta, elk, hnf6

Erg MASO

[foxN2/3, gcm, pmar1, soxC, tbr, z48 (18-24 h)]

Ets1 MASO

delta, endo16, eve, foxb, gcm, pmar1, sm30, tbr, [jun, krl, pks, z48 (18-24 h)]

Eve MASO

alx1, cyclophilin, dri, ets1, foxc, gatac, gatac, gsc, hmx, msp130, not, otx a, otx b1/2, otx b3, pmar1, sm30, soxb1, tbr, [foxG, msx, myc, notch, soxC (15-27 h)]

FoxA MASO

b1/2otx, hmx, not (0-48 h), nrl, otx a, pks, tbr, [brn1/2/4, delta, eve, hox11/13b, wnt8 (18-27, 32, 48 h)], [blimp1, foxc (18, 24, 32, 48 h)], [alx1, blimp1b, dac, elk, foxN2/3, foxP, hesC, hnf1, msx, myc, notch, otxb1/2, soxB1, soxC, tgif, unc4.1, z188 (18-27 h)]

FoxB MASO

cyclophillin, endo16, ets1, ficolin, foxa, gatae, hox11/13b, sm27, sm50, tbr, wnt8

FoxN2/3 MASO

[cyclophillin, dri, foxA, foxN2/3, foxb, gatac, gcm, hex, hnf6, jun, krl, msp130, msp130L, not, pm27, pmar1, sm50, snail, soxC, tbr, tgif, z48 (18-24 h)]

GataC MASO

bra, capk, delta, dpt, elk, eve, gatae, gcm, not, pks

GataE MASO

??????, blimp1, capk, dec, dri, elk, ets1, eve, ferritin, gatae, gcm, hmx, nk1, otx a, [alx1, dac, delta, foxN2/3, hesC, soxB1, soxC (18-27 h)]

Gcm MASO

capk, dec, delta, elk, gatac, gatae, hmx, not, nrl

Gsc MASO

alx1, blimp1, bra, decorin, delta (in pmc's), dri, ets1, eve, foxb, fvmo, gatac, gcm, gsc, hmx, hnf6, krl, pks, pmar1, tbr, wnt8, z12-1 (17, 23 h)

Hex MASO

[dri, foxA, gcm, gsc, jun, krl, pmar1, tbr, z48 (18-24 h)]

Hnf1 MASO

[Brn1/2/4, alx1, blimp1b, bra, dac, delta, elk, endo16, eve, foxG, foxN2/3, foxP, foxa, foxb, gatac, gatae, gcm, hh, hox11/13b, krl, msx, myc, notch, otxb1/2, soxC, soxb1, tgif, unc4.1, wnt8, z188 (24-27 h)]

Hnf6 MASO

alx1, blimp1, bra, cyclophillin, delta, dri (in pmc's), elk, ets1, eve, foxa, gatae, gcm, hnf6 (in pmc's), otx a, pmar1, tbr, wnt8, [foxb, krl, z12-1 (19-20 h)]

Hox11/13b MASO

blimp1, otx a, otx b, soxb1, wnt8, [Brn1/2/4, alx1, dac, delta, elk, hnf6, otxb1/2, soxC, z188 (18-27 h)]

Krl MASO

alx1, blimp1, bra, dec, delta (12, 18-27 h), dri, ets1, eve, eve, gatae, gcm, gsc, hmx, krl, lim1, nrl, otx b1/2, pm27, pmar1, sm50, tbr, wnt8, z12-1, [dac, foxN2/3, foxP, gataC, hesC, msx, myc, notch, soxC, z188 (18-27 h)]

MutantSu(H) MOE

[endo16, sm50 (18, 24, 30 h)]

Myc MASO

[blimp1b, bra, dac, delta, endo16, eve, foxG, foxN2/3, foxP, gataC, gataE, gcm, hesC, hnf6, notch, soxB1, soxC, wnt8, z188 (18-27 h)]

N MASO

[foxa, foxb (18-27, 29, 41 h)], [bra, eve (21, 24-27, 29, 41 h)], [espl1, gatae, hmx, nrl, su (21, 29, 41 h)], [brn1/2/4, dac, foxN2/3, foxP, hesC, hh, myc, soxB1, soxC, wnt8 (18-27 h)]

Otx-En

dec, delta, elk, eve, gcm, otx a, pks, tbr

OtxHD MASO

[alx1, blimp1b, bra, dac, delta, elk, eve, foxN2/3, foxP, gatae, gcm, hnf6, hox11/13b, krl, myc, notch, otxb1/2, soxC, soxb1, unc4.1, wnt8, z188 (18-27 h)]

Otxa MASO

[alx1, blimp1b, bra, endo16, eve, foxG, foxP, foxa, foxb, gatac, gatae, gcm, hox11/13b, myc, soxC, soxb1, tgif, unc4.1, z188 (18-27 h)]

Pmar1 MOE

blimp1, elk, foxa, hnf6, krl, sm30, wnt8

Pmar1-En

blimp1, elk, foxa, hnf6, sm30, wnt8

SoxC MASO

[cyclophillin, dri, erg, ets1, foxO, hex, jun, msp130L, not, nrl, pm27, pmar1, sm50, snail, tbr, tel, vegfrII, z48 (18-24 h)], [alx1, blimp1b, bra, dac, delta, elk, endo16, eve, foxA, foxG, foxN2/3, foxP, foxb, gataC, gatae, gcm, hh, hnf1, hnf6, hox11/13b, krl, msx, myc, notch, otxb1/2, soxb1, unc4.1, wnt8, z188 (18-27 h)]

Soxb1 MASO

blimp1, bra, dec, dpt, dri, elk, endo16, foxa, foxb, foxc, gatac, krl, nrl, pmar1, wnt8, z12-1, [delta, gatae, gcm, hox11/13b, tbr (0-16 h)]

Soxb1 MOE

blimp1, dri, endo16, hnf6, tbr

Soxb1-En

alx1 (12 h), [bra, delta, endo16, ets-1, eve, foxa, foxb, gatac, gcm, hox11/13b, krl, msp130, pm27, sm50, wnt8 (18, 24 h)]

Tbr MASO

alx1, cyclophilin, delta, endo16, ets1, ets1, eve, ficolin, gatae, gcm, msp130, msp130L, pm27, [cyclophillin, foxA, foxN2/3, foxO, gatac, hex, jun, not, pks, pmar1, soxC, tel, vegfrII, z48 (18-24 h)]

Tel MASO

[cyclophillin, dri, erg, ets1, ficolin, foxA, foxB, foxN2/3, foxO, gcm, hex, hnf6, jun, krl, msp130, msp130L, not, pks, pmar1, pmar1, soxC, tbr, vegfrII, z48 (18-24 h)]

Tgif MASO

[cyclophillin, ets1, jun, pmar1, tbr, tel (18-24 h)], [dac, delta, elk, endo16, eve, gatac, hesC, hox11/13b, msx, myc, notch, soxC, wnt8, z188 (18-27 h)]

Footnotes

1Must be affected indirectly via intercellular signaling because Bra is not present in cells where these genes are active.

2At 30 h affected indirectly via cell signaling, since at 30 h Dri and Gsc are expressed only in OE.

3Thought to be indirect input, via GataE.

4Probably via GataC.

5Probably via Bra.

6Probably in OE where both Elk and Lim1 are expressed then.

7Probably indirect via Gcm.

8Probably indirect via gcm.

9The inputs inferred from effects on endo16.

10Effect on endo16 is via Ui since no necessary GataE site in endo16.

11Probably via ets1; based on ECRA.

12Indirect, because rescued by blimp1 MOE.

14Probably indirect via elk.

15Weak effect 18 h only, probably not significant, since wnt8 expression is disappearing in gatae domain at 18 h. Effect seen is probably via Otx which represses wnt8 in this period.

17Likely indirect via gatae.

18Late Krl effects likely to be indirect results of effects of Krl loss on endomesoderm specification (Howard et al., 2000).

19Obviously indirect via pmar1.

20Only when dri is expressed in OE (>30 h).

21Possibly indirect via, because if there were an Otx site in gatac gene effect would have been seen earlier than 24 h.

22Must be indirect because direct sm50 inputs are known.

23Normalized to different standards in same run, i.e., ubiquitin and 18S rRNA.

24 alx1 expressed specifically in pmc's; discovered by Ettensohn et al.

26In collaboration with R. and L. Angerer who provided the samples measured.

27Likely an artifact of expressing Blimp1-En MOE pmc's, since foxb is expressed only in pmc's at this stage (i.e., there could be a later interaction of Blimp1 and Soxb in hindgut where they are both expressed after gastrulation).

28Weak effect likely indirect since gatac is expressed in smc's at 27 h and foxb in pmc's, later hindgut on oral side (plus oral ectoderm).

30Not indirect via GataE because N MASO does not affect gatac though dnN does.

31Indirect effects on gatac does not turn on until after Tcf input is faded out, but all other inputs depend on endomesoderm specification.

32Effect on initial phase of gatac expression, before it becomes exclusive with gcm (oral vs aboral and lateral).

33Could be indirect via Ets1 effect on tbr; effect of Ets1 on foxb is stronger than tbr effect on foxb.

34At least early (<24 h) effects on the three fvmo genes probably via gcm.

35Via dri (see Amore et al., 2002).

37Implies late blastula pmc domain to mesoderm indirect effect on oral side, where gatac is then expressed in mesoderm: not yet understood.

38Since Gsc is a repressor (Angerer et al.) implies existence of mid-late blastula repressor of skeletogenic function controlled by gsc: perhaps a timing device.

40Very possibly indirect via dri.

41Unlikely a direct transcriptional effect, since eve expression is not affected by Soxb1-Eng MOE.

42Possibly indirect.

43Likely via dri.

45Probably in OE because most gsc expression at 24 h is there.

47Double perturbation results show both inputs, Alx1 and Ets1, are required when indicated.

48Data for mesenchyme blastula stage of Lytechinus variegatus

49Probably Indirect

50Unc4.1 is expressed in the aboral veg1 ectoderm, starting at 24h; effect must be indirect